Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty

Jiang Du; Chenhuan Lu; Jing Wang

doi:doi:10.11648/j.js.20200806.16

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Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty

Jiang Du, Chenhuan Lu, Jing Wang

Published in Journal of Surgery (Volume 8, Issue 6)

Received: 1 November 2020 Accepted: 19 November 2020 Published: 30 November 2020

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Abstract

Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.

Published in	Journal of Surgery (Volume 8, Issue 6)
DOI	10.11648/j.js.20200806.16
Page(s)	204-208
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Percutaneous Vertebroplasty, Osteoporotic Vertebral Compression Fractures, Recurrent Fractures, Risk Factors

References

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APA Style

Jiang Du, Chenhuan Lu, Jing Wang. (2020). Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. Journal of Surgery, 8(6), 204-208. https://doi.org/10.11648/j.js.20200806.16

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ACS Style

Jiang Du; Chenhuan Lu; Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J. Surg. 2020, 8(6), 204-208. doi: 10.11648/j.js.20200806.16

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AMA Style

Jiang Du, Chenhuan Lu, Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J Surg. 2020;8(6):204-208. doi: 10.11648/j.js.20200806.16

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@article{10.11648/j.js.20200806.16,
  author = {Jiang Du and Chenhuan Lu and Jing Wang},
  title = {Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty},
  journal = {Journal of Surgery},
  volume = {8},
  number = {6},
  pages = {204-208},
  doi = {10.11648/j.js.20200806.16},
  url = {https://doi.org/10.11648/j.js.20200806.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20200806.16},
  abstract = {Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.},
 year = {2020}
}

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TY  - JOUR
T1  - Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty
AU  - Jiang Du
AU  - Chenhuan Lu
AU  - Jing Wang
Y1  - 2020/11/30
PY  - 2020
N1  - https://doi.org/10.11648/j.js.20200806.16
DO  - 10.11648/j.js.20200806.16
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 204
EP  - 208
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20200806.16
AB  - Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.
VL  - 8
IS  - 6
ER  -

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Author Information

Jiang Du

Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China
Chenhuan Lu

Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China
Jing Wang

Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou, China

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APA Style

Jiang Du, Chenhuan Lu, Jing Wang. (2020). Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. Journal of Surgery, 8(6), 204-208. https://doi.org/10.11648/j.js.20200806.16

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ACS Style

Jiang Du; Chenhuan Lu; Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J. Surg. 2020, 8(6), 204-208. doi: 10.11648/j.js.20200806.16

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AMA Style

Jiang Du, Chenhuan Lu, Jing Wang. Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty. J Surg. 2020;8(6):204-208. doi: 10.11648/j.js.20200806.16

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@article{10.11648/j.js.20200806.16,
  author = {Jiang Du and Chenhuan Lu and Jing Wang},
  title = {Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty},
  journal = {Journal of Surgery},
  volume = {8},
  number = {6},
  pages = {204-208},
  doi = {10.11648/j.js.20200806.16},
  url = {https://doi.org/10.11648/j.js.20200806.16},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20200806.16},
  abstract = {Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Analysis of Risk Factors of Recurrent Vertebral Fractures After Percutaneous Vertebroplasty
AU  - Jiang Du
AU  - Chenhuan Lu
AU  - Jing Wang
Y1  - 2020/11/30
PY  - 2020
N1  - https://doi.org/10.11648/j.js.20200806.16
DO  - 10.11648/j.js.20200806.16
T2  - Journal of Surgery
JF  - Journal of Surgery
JO  - Journal of Surgery
SP  - 204
EP  - 208
PB  - Science Publishing Group
SN  - 2330-0930
UR  - https://doi.org/10.11648/j.js.20200806.16
AB  - Background: Investigate the risk factors of recurrent vertebral compression fractures after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures (OVCF). Method: Data of 401 patients with osteoporotic vertebral compression fractures treated by PVP from March 2013 to June 2018 were retrospectively analyzed, and were divided into re-fracture group and nonre-fracture group according to the postoperative recurrence of vertebral compression fractures. The following parameters were observed, including age, gender, bone mineral density (BMD), correction degree of kyphosis, recovery degree of vertebral height, amount of bone cement injected, Pfirrmann classification of adjacent intervertebral disc of hurt vertebral, and bone cement leakage in intervertebral disc. Then, the above parameters were statistically analyzed by univariate and multivariate analysis to explore the risk factors of vertebral recurrent fracture after PVP. Result: Among 401 patients, 34 (34 /401, 8.4%) recurred OVCF after PVP. Statistical analysis showed that the risk of recurrent vertebral fracture increased by 3.732 times (95% CI 1.107-12.581) when Pfirrmann classification of adjacent intervertebral disc was in degeneration grade. The risk of recurrent vertebral fracture was significantly increased by 31.818 times (95% CI 13.384-75.640) when bone cement leakage occurred in intervertebral disc. Conclusion: Pfirrmann classification of adjacent intervertebral disc and bone cement leakage in intervertebral disc are significantly correlated with the recurrence of vertebral fracture after PVP. In PVP operation, avoiding the bone cement leakage in intervertebral disc can significantly reduce the recurrence of vertebral compression fractures.
VL  - 8
IS  - 6
ER  -

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